NF-κB RelA Is Required for Hepatoprotection during Pneumonia and Sepsis
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چکیده
منابع مشابه
Functions and Regulation of NF- B RelA during Pneumococcal Pneumonia
Eradication of bacteria in the lower respiratory tract depends on the coordinated expression of proinflammatory cytokines and consequent neutrophilic inflammation. To determine the roles of the NFB subunit RelA in facilitating these events, we infected RelA-deficient mice (generated on a TNFR1-deficient background) with Streptococcus pneumoniae. RelA deficiency decreased cytokine expression, al...
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ژورنال
عنوان ژورنال: Infection and Immunity
سال: 2019
ISSN: 0019-9567,1098-5522
DOI: 10.1128/iai.00132-19